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The Lysine 65 Residue in HIV-1 Reverse Transcriptase Operate and in Nucleoside Analog Drug Resistance. Cigarettes additionally promote acid production in the stomach, so there’s more to pass via the sphincter within the first place. Garforth SJ, Lwatula C, Prasad VR. The Lysine sixty five Residue in HIV-1 Reverse Transcriptase Perform and in Nucleoside Analog Drug Resistance. Garforth, S.J.